Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of multiple myeloma. Its synthesis or analyze is very important for making sure the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor while in the synthesis of abiraterone acetate, a drug used in the cure of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A vital compound during the synthesis of imatinib, a drug that targets distinct forms of most cancers, like chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the manufacturing course of action and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to take care of breast most cancers, and Lenvatinib intermediate these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Utilized in the procedure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have several purposes, such as antiviral properties.
Vildagliptin Intermediates: Utilized in the manufacture of 4 vildagliptin, an oral drug for variety 2 diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be Utilized in food stuff, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication employed to handle variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).